Decision dynamics in cortico-basal ganglia-thalamic networks


Collaborators: Tim Verstynen, Eric Yttri (Carnegie Mellon U.), Cati Vich (U. de les Illes Balears), Jyotika Bahuguna (U. Strasbourg)


Current trainees:   Zhuojun Yu (CMU), Cristina Giossi & Alex G. O'Hare (UIB), Kayla Kraueter (Pitt)
How do the basal ganglia interact with cortical and thalamic neurons to influence our decision-making, action selection, and movements?  How do we learn from rewards and reward omissions?  
Some recent publications:
 1.   B. Sosis and J.E. Rubin, “Calculation of expected reward rate in a two-alternative decision process”, SIAM. J. Appl. Math., 85(2), 433-455, 2025 (Erratum: SIAM J. Appl. Math. 85 (3), 1314-1314, 2025)  
2.    M. Clapp, J. Bahuguna, C. Giossi, J.E. Rubin, T. Verstynen, C. Vich, “CBTPy: An extensible cortico-basal ganglia-thalamic framework for modeling biological decision making”, PLoS One, 20(1), e0310367, 2025 
3.     C. Giossi, J. Bahuguna, J.E. Rubin, T. Verstynen, C. Vich, “Arkypallidal neurons in the external globus pallidus can mediate inhibitory control by altering competition in the striatum”, Proc. Natl. Acad. Sci. USA 121(47)e2408505121, 2024